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PeptideHormone

Octreotide vs Lanreotide

A long-acting somatostatin analog used to suppress GH and other hormones. A depot somatostatin analog, similar in action to octreotide. Side by side: type, evidence tier, receptor, molecular weight, and half-life — the same fields as each monograph, rearranged so the engineering difference is visible.

Octreotide
Lanreotide
Also known asSandostatinSomatuline
TypeAnalogAnalog
EvidenceEstablishedEstablished
FamilyGrowth & repairGrowth & repair
ClassSomatostatin analog (cyclic octapeptide)Somatostatin analog (cyclic octapeptide)
ReceptorSomatostatin receptors (SSTR2 and SSTR5 preferential)Somatostatin receptors (SSTR2 and SSTR5 preferential)
Molecular weight~1,019.2 Da~1,096.3 Da
Half-life
~1.5 h (subcutaneous; LAR depot ~monthly)
Model dosing
depot-dominant (autogel acts over weeks)
Based onSomatostatinSomatostatin

Half-life bars are on a logarithmic scale across the molecules shown. Reference values for the native or representative form — educational only, not medical or dosing advice.

Common questions

What is the difference between Octreotide and Lanreotide?
Octreotide is an engineered analog based on Somatostatin; Lanreotide is an engineered analog based on Somatostatin. Octreotide signals at Somatostatin receptors (SSTR2 and SSTR5 preferential); Lanreotide signals at Somatostatin receptors (SSTR2 and SSTR5 preferential).
How do the half-lives of Octreotide and Lanreotide compare?
The reported circulating half-life of Octreotide is ~1.5 h (subcutaneous; LAR depot ~monthly); Lanreotide is depot-dominant (autogel acts over weeks). These are reference values for the native or representative form — educational only, not dosing advice.
Is Octreotide the same as Sandostatin?
Sandostatin is a brand name of Octreotide. This comparison describes the molecules, not branded products.

Prefer the other order? Lanreotide vs Octreotide. Or open the interactive comparison tool to add more molecules.