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PeptideHormone

Lanreotide vs Octreotide

A depot somatostatin analog, similar in action to octreotide. A long-acting somatostatin analog used to suppress GH and other hormones. Side by side: type, evidence tier, receptor, molecular weight, and half-life — the same fields as each monograph, rearranged so the engineering difference is visible.

Lanreotide
Octreotide
Also known asSomatulineSandostatin
TypeAnalogAnalog
EvidenceEstablishedEstablished
FamilyGrowth & repairGrowth & repair
ClassSomatostatin analog (cyclic octapeptide)Somatostatin analog (cyclic octapeptide)
ReceptorSomatostatin receptors (SSTR2 and SSTR5 preferential)Somatostatin receptors (SSTR2 and SSTR5 preferential)
Molecular weight~1,096.3 Da~1,019.2 Da
Half-lifedepot-dominant (autogel acts over weeks)
~1.5 h (subcutaneous; LAR depot ~monthly)
Model dosing
Based onSomatostatinSomatostatin

Half-life bars are on a logarithmic scale across the molecules shown. Reference values for the native or representative form — educational only, not medical or dosing advice.

Common questions

What is the difference between Lanreotide and Octreotide?
Lanreotide is an engineered analog based on Somatostatin; Octreotide is an engineered analog based on Somatostatin. Lanreotide signals at Somatostatin receptors (SSTR2 and SSTR5 preferential); Octreotide signals at Somatostatin receptors (SSTR2 and SSTR5 preferential).
How do the half-lives of Lanreotide and Octreotide compare?
The reported circulating half-life of Lanreotide is depot-dominant (autogel acts over weeks); Octreotide is ~1.5 h (subcutaneous; LAR depot ~monthly). These are reference values for the native or representative form — educational only, not dosing advice.
Is Lanreotide the same as Somatuline?
Somatuline is a brand name of Lanreotide. This comparison describes the molecules, not branded products.

Prefer the other order? Octreotide vs Lanreotide. Or open the interactive comparison tool to add more molecules.