A synthetic anxiolytic/nootropic peptide derived from tuftsin. Structurally it is Synthetic heptapeptide (tuftsin analog).

How strong is the evidence for Selank?

PeptideHormone grades Selank at the "Limited" evidence tier — the evidence is sparse, older, or mostly community-reported. It is catalogued as a community research peptide outside the approved-drug system, and the tier is an editorial judgment about the public literature that can change as the science does.

What is the half-life of Selank?

The reported circulating half-life of Selank is Minutes in plasma (CNS effects outlast).

Selank

A synthetic anxiolytic/nootropic peptide derived from tuftsin.

Research peptideLimited

An endogenous fragment given a longer life by synthesis. The neuropeptide biology is real; the human evidence is thin, and mostly from one research tradition.

Identity

Class: Synthetic heptapeptide (tuftsin analog)
Source: Synthetic; based on the immunopeptide tuftsin
Receptor: No single established receptor; effects on GABA/serotonin and immune signaling proposed

Key properties

Evidence floorPreclinicalREF1PRE1

Molecular weight

≈ 751.9 Da

REF

Half-life (native)

Minutes in plasma (CNS effects outlast)

PRE

Approximate values for the native hormone; engineered analogs are often deliberately larger and far longer-acting. Each figure carries its own provenance tier, and the floor is the weakest of them - the Standard.

Mechanism

Selank is a synthetic heptapeptide based on the immune-active fragment tuftsin, developed (largely in Russia) as an anxiolytic and nootropic. Proposed effects touch GABAergic, serotonergic, and immune signaling, but well-controlled independent human evidence is limited.

Reference notes

Derived from tuftsin, an endogenous immunomodulatory peptide fragment.
Developed primarily outside large international trial programs; independent evidence is limited.
Mechanism is proposed across several systems rather than firmly established.

Common questions

What is Selank?: A synthetic anxiolytic/nootropic peptide derived from tuftsin. Structurally it is Synthetic heptapeptide (tuftsin analog).
How does Selank work?: Selank is a synthetic heptapeptide based on the immune-active fragment tuftsin, developed (largely in Russia) as an anxiolytic and nootropic. Proposed effects touch GABAergic, serotonergic, and immune signaling, but well-controlled independent human evidence is limited.
How strong is the evidence for Selank?: PeptideHormone grades Selank at the "Limited" evidence tier — the evidence is sparse, older, or mostly community-reported. It is catalogued as a community research peptide outside the approved-drug system, and the tier is an editorial judgment about the public literature that can change as the science does.
What is the half-life of Selank?: The reported circulating half-life of Selank is Minutes in plasma (CNS effects outlast).

Selected literature

Curated peer-reviewed reviews, sourced from PubMed. Selected for relevance, not exhaustive — open any entry on PubMed for the full record and its primary citations.

1.Tuftsin - Properties and Analogs · Current medicinal chemistry, 2017 · PMID 28745220

External references

Selank in the public knowledge graph — the same entity resolved across the authoritative chemistry and protein databases.