Lanreotide vs Somatostatin
A depot somatostatin analog, similar in action to octreotide. The brake on the growth-hormone axis — and much else. Side by side: type, evidence tier, receptor, molecular weight, and half-life — the same fields as each monograph, rearranged so the engineering difference is visible.
Lanreotide | Somatostatin SST | |
|---|---|---|
| Also known as | Somatuline | — |
| Type | Analog | Endogenous |
| Evidence | Established | Established |
| Family | Growth & repair | Growth & repair |
| Class | Somatostatin analog (cyclic octapeptide) | Cyclic peptide (14 and 28 aa forms) |
| Receptor | Somatostatin receptors (SSTR2 and SSTR5 preferential) | Somatostatin receptors SSTR1–SSTR5 |
| Molecular weight | ~1,096.3 Da | ~1,637.9 Da |
| Half-life | depot-dominant (autogel acts over weeks) | |
| Based on | Somatostatin | Native hormone |
Half-life bars are on a logarithmic scale across the molecules shown. Reference values for the native or representative form — educational only, not medical or dosing advice.
Common questions
- What is the difference between Lanreotide and Somatostatin?
- Lanreotide is an engineered analog based on Somatostatin; Somatostatin is an endogenous hormone. Lanreotide signals at Somatostatin receptors (SSTR2 and SSTR5 preferential); Somatostatin signals at Somatostatin receptors SSTR1–SSTR5.
- How do the half-lives of Lanreotide and SST compare?
- The reported circulating half-life of Lanreotide is depot-dominant (autogel acts over weeks); Somatostatin is ~1–3 min (very short). These are reference values for the native or representative form — educational only, not dosing advice.
- Is Lanreotide the same as Somatuline?
- Somatuline is a brand name of Lanreotide. This comparison describes the molecules, not branded products.
Prefer the other order? Somatostatin vs Lanreotide. Or open the interactive comparison tool to add more molecules.