Ghrelin vs Ipamorelin
Stomach-derived hunger signal that also amplifies GH pulses. A selective GH secretagogue that mimics ghrelin at GHS-R. Side by side: type, evidence tier, receptor, molecular weight, and half-life — the same fields as each monograph, rearranged so the engineering difference is visible.
Ghrelin | Ipamorelin | |
|---|---|---|
| Also known as | — | — |
| Type | Endogenous | Analog |
| Evidence | Established | Preclinical |
| Family | Growth & repair | Growth & repair |
| Class | Acylated peptide hormone (28 aa) | Synthetic pentapeptide GH secretagogue (GHRP) |
| Receptor | Growth hormone secretagogue receptor (GHS-R1a) | Growth hormone secretagogue receptor (GHS-R1a) |
| Molecular weight | ~3,370.9 Da | ~711.9 Da |
| Half-life | ||
| Based on | Native hormone | Ghrelin |
Half-life bars are on a logarithmic scale across the molecules shown. Reference values for the native or representative form — educational only, not medical or dosing advice.
Common questions
- What is the difference between Ghrelin and Ipamorelin?
- Ghrelin is an endogenous hormone; Ipamorelin is an engineered analog based on Ghrelin. Ghrelin signals at Growth hormone secretagogue receptor (GHS-R1a); Ipamorelin signals at Growth hormone secretagogue receptor (GHS-R1a).
- How do the half-lives of Ghrelin and Ipamorelin compare?
- The reported circulating half-life of Ghrelin is ~30 min (acyl-ghrelin); Ipamorelin is ~2 h. These are reference values for the native or representative form — educational only, not dosing advice.
Prefer the other order? Ipamorelin vs Ghrelin. Or open the interactive comparison tool to add more molecules.