CJC-1295 vs Ipamorelin
A long-acting GHRH analog engineered to stretch GH pulses. A selective GH secretagogue that mimics ghrelin at GHS-R. Side by side: type, evidence tier, receptor, molecular weight, and half-life — the same fields as each monograph, rearranged so the engineering difference is visible.
CJC-1295 | Ipamorelin | |
|---|---|---|
| Also known as | — | — |
| Type | Analog | Analog |
| Evidence | Limited | Preclinical |
| Family | Growth & repair | Growth & repair |
| Class | GHRH(1-29) analog (with or without a drug-affinity complex) | Synthetic pentapeptide GH secretagogue (GHRP) |
| Receptor | GHRH receptor (GHRHR), a class B GPCR | Growth hormone secretagogue receptor (GHS-R1a) |
| Molecular weight | ≈3,647 Da | ~711.9 Da |
| Half-life | ~6-8 days (DAC form); ~30 min without DAC | |
| Based on | Growth-hormone-releasing hormone | Ghrelin |
Half-life bars are on a logarithmic scale across the molecules shown. Reference values for the native or representative form — educational only, not medical or dosing advice.
Common questions
- What is the difference between CJC-1295 and Ipamorelin?
- CJC-1295 is an engineered analog based on Growth-hormone-releasing hormone; Ipamorelin is an engineered analog based on Ghrelin. CJC-1295 signals at GHRH receptor (GHRHR), a class B GPCR; Ipamorelin signals at Growth hormone secretagogue receptor (GHS-R1a).
- How do the half-lives of CJC-1295 and Ipamorelin compare?
- The reported circulating half-life of CJC-1295 is ~6-8 days (DAC form); ~30 min without DAC; Ipamorelin is ~2 h. These are reference values for the native or representative form — educational only, not dosing advice.
Prefer the other order? Ipamorelin vs CJC-1295. Or open the interactive comparison tool to add more molecules.